OVA1 Next Generation is a qualitative serum tumor marker panel that includes CA-125 II, transferrin, transthyretin (prealbumin), apolipoprotein A-1, and beta2-microglobulin, and ROMA is an algorithm that includes CA-125, HE4, and menopausal status [4]. The gene discussed is WFDC2; the disease is neoplasm.