ITIH3 and posterior cortical atrophy: They found that the levels of exosome-derived LRG1 and inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3) were 1.7-fold and 2.04-fold higher in the CRPC group than those in the PCa group, respectively, suggesting that LRG1 and ITIH3 could serve as potential molecular diagnostic markers for CRPC.