Based on the symptoms of fever and abdominal pain, along with leukocytosis and a left shift in the differential count, elevated C-reactive protein(CRP) and procalcitonin as markers of infection, thickening of the peritoneum, and exudative ascites, a diagnosis of post-hepatitis cirrhosis complicated with spontaneous bacteria peritonitis was made and the patient received cefoperazone monotherapy for 48 hours followed by combined with vancomycin to fight against bacterial infection. This evidence concerns the gene CRP and infection.