AKT1 and non-small cell lung carcinoma: Xu et al. identified C-C motif ligand 2 (CCL2), a well-known CC chemokine involved in tumor progression, as a promoter of metastasis and epithelial–mesenchymal transition in non-small cell lung cancer through the PI3K/Akt/mTOR and autophagy pathways (Xu et al., 2023).