Mitochondrial elongation factor 2 (MIEF2) is involved in mitochondrial fission, and its expression is increased in ovarian cancer, which enhances the Warburg effect in ovarian cancer cells, and promotes oxidative phosphorylation (OXPHOS) towards aerobic glycolysis, and it is crucial to ovarian cancer cell’s migration and invasion [23]. The gene discussed is MIEF2; the disease is ovarian cancer.