A conserved 90-amino acid peptide encoded by lncRNA AFAP1-AS1 (actin filament associated protein 1 antisense RNA 1) is located on mitochondria, which is called as an AFAP1-AS1 translated mitochondrial‐localized peptide (ATMLP), promoting the malignant phenotype of non-small cell lung cancer. Here, AFAP1 is linked to non-small cell lung carcinoma.