ALT 81 U/L, AST 46 U/L, GGT 85 U/L, AFU 89 U/L; AFP 17.5 ug/L, AFP-L3% 28.1 %, AFP-L3 (+); Systemic rheumatic disease autoantibodies SSA, SSB, Jo-1, RNP, Sm, Scl-70, ACA, dsDNA, NA, HA, RPPA, PCNA, PM-Scl (-); MR revealed cirrhosis, multiple sclerotic nodules, parapancreatic lymph nodes, fatty liver, and cholecystitis. The gene discussed is AFP; the disease is Cholecystitis.