Then qRT-PCR was performed to demonstrate the mRNA level of Ki67, CDK2, and cyclin E1, the same as WB results, all those three factors were also upregulated in CRSwNP (Figure 3 Ki67, p < 0.0001; CDK2 and cyclinE1, p < 0.05). Here, CCNE1 is linked to chronic rhinosinusitis with nasal polyps.