Genes that were differentially expressed between cancer cells from the two primary tumours included upregulation of ENSCAFG00000037735 (TMSB4X) and downregulation of CSRP2, LGALS2, and C15orf48 in Patient 1 compared to Patient 2 (Fig. 4A, Supplementary Table 8). The gene discussed is TMSB4X; the disease is neoplasm.