Under normal conditions, activated EGFR plays a crucial role in maintaining epithelial tissue, regulating cell proliferation, differentiation, division, migration, survival, and apoptosis.16 However, deregulation of the EGFR pathway results in cellular dysfunctions and pathologies, including increased proliferation, motility, angiogenesis, vascular mimicry, and invasiveness, which support tumor development.17 The delivery of boron by targeting EGFR has already been reported in BNCT. The gene discussed is EGFR; the disease is neoplasm.