CD4 and cancer: PWH with CD4+ cell count < 200/mm3 at cART initiation showed the highest cumulative cancer incidence, about 4% after 5 years from first cART, as compared to 3% of those with CD4 cell counts between 200 and 349/mm3 at cART initiation and 2% of those with CD4+ cell counts >350/mm3 (Gray's test p < .001).