Bacteremia (odds ratio (OR): 32.232, 95%CI: [2.558-406.068], P = 0.007), CRP > 162.375 mg/L (OR: 7.499, 95% CI: [2.044–27.513], P = 0.002), and delayed operation > 9.50 days (OR: 7.462, 95% CI: [1.828–30.459], P = 0.005),were high-risk factors for the occurrence of disseminated infection. This evidence concerns the gene CRP and bacterial infectious disease with sepsis.