It exhibits significant anti-tumor activity in treating multiple cancers, such as breast cancer, cervical cancer, colorectal cancer, lung cancer, papillary thyroid cancer, etc. Jin et al. found that curcumin suppressed cell proliferation and induced apoptosis in vitro, with the underlying mechanism involving the activation of miR-192-5p and inhibition of the PI3K/Akt pathway [55]. The gene discussed is AKT1; the disease is neoplasm.