LHX8 and neoplasm: Quantitative reverse transcription PCR (qRT-PCR) analysis revealed that BAT markers (UCP-1, TBX1, and LHX8) were significantly more expressed in periprostatic tumor fat compared with preprostate fat (UCP-1 fold change: 35.2 versus 1.30; p < 0.001), suggesting a higher presence of UCP-1 expressing BAT near prostate tumors.