UCP1 and Familial prostate cancer: Analysis of the open access University of California, Santa Cruz (UCSC) Genomic Online Resource database for the GDC The Cancer Genome Atlas Program (TCGA) Prostate Cancer (PRAD) cohort (n = 142) revealed an inverse relationship between UCP-1 expression and time to biochemical recurrence in patients with prostate cancer (hazard ratio, HR: 0.63, 95% confidence intervals, CI: 0.22–1.8, p = 0.160) (Fig. 4H).