As the NT-proANP tertiles had distinct levels of fasting insulin, insulin resistance scores and in the case of the subpopulation without CVDs, CKD, DM or related medications, BMI, suggesting insulin resistance and adiposity being negatively associated with NT-proANP levels, we next evaluated baseline NT-proANP levels according to liver adiposity status in the whole population and the two subpopulations, presented in Fig. 1. This evidence concerns the gene INS and Insulin resistance.