TSHR and Thyroid adenoma: Several lead TSH loci were mapped to nearby genes previously linked to thyroid function, including rs13030651-A (Beta = 0.035, P = 1.09×10-13) in the thyroid adenoma associated gene (THADA)36,37 and rs2160215 (Beta=0.065, P = 1.75 × 10-51) in thyrotropin receptor gene (TSHR)38,39.