There is mounting evidence indicating that inflammatory markers based on blood cell and serological indicators such as systemic immune-inflammation index (SII) [22,23], systemic inflammatory response index (SIRI) [24,25], CAR [26–28] and C-reactive protein-albumin-lymphocyte index (CALLY) [29] are significantly correlated with the risk of cardiovascular disease-related mortality. The gene discussed is ALB; the disease is cardiovascular disorder.