31 Vaduganathan Vaduganathan M M Docherty Docherty KF KF Claggett Claggett BL BL Jhund Jhund PS PS Boer Boer RA RA Hernandez Hernandez AF AF et al et al SGLT-2 Inhibitors in Patients with Heart Failure: A Comprehensive Meta-Analysis of Five Randomised Controlled Trials SGLT-2 Inhibitors in Patients with Heart Failure: A Comprehensive Meta-Analysis of Five Randomised Controlled Trials Lancet Lancet 2022 2022 400 400 10354 10354 757 757 767 767 10.1016/S0140-6736(22)01429-5 10.1016/S0140-6736(22)01429-5 36041474 36041474. The gene discussed is SLC5A2; the disease is heart failure.