Tspan7, a transmembrane glycoprotein functionally involved in many different viral infections [32] was downregulated 10 fold, and neuron development genes Tenm3 and Dpysl3 were down 19.4 fold and 26.8 fold respectively in Prol/CJ− vs Prol/Nl cells. This evidence concerns the gene DPYSL3 and viral infectious disease.