We also observed a significant correlation of PDGFRα and PDGFRβ overexpression with high tumor grades (G3-4) and significant tumor burden: the extent of tumor thrombosis (only PDGFRβ), pN+ (only PDGFRα), and M+ (only PDGFRβ) stages, including metastases to the adrenal glands (PDGFRβ). This evidence concerns the gene PDGFRA and neoplasm.