Myeloid cell trafficking to tumours depends on PI3Kγ‐mediated integrin activation, and subsequent myeloid cell recruitment and tumour inflammation depend on PLCγ, CalDAG‐GEFI and II, Rap1a, RIAM, talin, paxillin and myosin light chain kinase [65, 66]. The gene discussed is RAP1A; the disease is neoplasm.