FN1 and neoplasm: Previous studies have demonstrated that F. nucleatum can promote CRC development, metastasis, and chemoresistance, and that eliminating Fn is beneficial for tumor inhibition.[4] Thus, the treatment effect of SynCom was examined using the AOM‐DSS‐induced CRC mouse model, including Low‐SynCom and High‐SynCom groups (Figure5A).