TNF and periodontitis: Functionally, in addition to the function of enriching and releasing growth factors, CCS‐RSF@PRP can remarkably scavenge reactive oxygen species (ROS), neutralize endotoxin lipopolysaccharide (LPS), and proinflammatory cytokines (TNF‐α, IFN‐γ and IL‐1β), inhibit M1 macrophage polarization and induce M2 macrophage polarization, thus blocking the chronic inflammatory feedback loop in the periodontitis.