FN1 and neoplasm: Further experiments reveal that NM@PLGA‐MTI‐OXA reverses the Fn‐induced epithelial‐mesenchymal transition (EMT) in tumor cells during metastasis and remodels the immunosuppressive microenvironment, suppressing colorectal cancer and liver metastasis development while minimizing broad‐spectrum damage to the commensal microbiota.