CCN2 and Mental deterioration: Among the KD genes whose network neighborhoods showed top fold enrichment rankings for candidate genes with multiple effects are Mpped1 and Ctgf discussed above, as well as Dlgap2, whose network neighborhood has the highest fold enrichment for genes with outgoing and combined effects and is associated with age‐related cognitive decline (Figures S24–S26 and Table S5, Supporting Information).[64] By identifying the relationships between KD and candidate genes, it also allows us to elucidate the regulatory networks involved in mediating the spreading of α‐Syn pathology.