CD274 and neoplasm: Receiver operating characteristic (ROC) analyses indicated that the TMEclassifier outperformed PD‐L1 combined positive score (CPS), TIDE score,[26] and other two Tumor classification system[27] in predicting both ICBs response rate (ORR) and progression‐free survival in TIMES001 clinical trial (Figure 6D,E; Figure S5A–D, Supporting Information).