EIF4EBP1 and esophageal squamous cell carcinoma: c‐Myc, a multifunctional transcription factor, significantly influences tumor development and treatment resistance in ESCC by promoting the acquisition of CSC‐like characteristics.[32, 33] In this study, we demonstrated that high QSOX2 activating mTOR/4E‐BP1/c‐Myc pathway.