Biomarkers have shown significant promise in prognostication following acute respiratory distress syndrome (ARDS) (6–10) and sepsis (11, 12): interleukin (IL)-6, IL-8 (otherwise known as C-X-C motif ligand-8 or CXCL8), and tumor necrosis factor receptor 1 (TNFR1). Here, TNFRSF1A is linked to Sepsis.