Neutralizing Antibodies: Knockdown of miR-125a-5p gene in mice with silicosis by administration of miR-125a-5p antibody slows down silica-induced pulmonary fibrosis in mice by regulating T-cell subset occupancy (6); a model of dermatofibrosis in mice with hypochlorite showed that acazicolcept reduced inflammatory cells infiltration in the skin lesions and decreased fibrosis levels in the spleen and lung by decreasing CD69 and PD-1 expression of CD4+T cells, as well as reducing fibrosis in the spleen and lung, as compared with Fc-control mice. This evidence concerns the gene PDCD1 and pulmonary fibrosis.