On the other hand, serum IL-6/IL-10 ratio has been suggested as a biomarker for diagnosing and assessing the severity of primary open-angle glaucoma (51), and the IL-10/IL-6 ratio in both vitreous and aqueous humor has been used to diagnose vitreoretinal lymphoma (VRL) (52, 53), serving as a prioritized auxiliary diagnostic tool to differentiate VRL from uveitis (54). Here, IL10 is linked to open-angle glaucoma.