PAX8 and soft tissue neoplasm: Recently, it has also been reported in the literature that Pax-2 and Pax-8 exhibit a certain expression rate in other soft tissue tumors, such as synovial sarcoma (11), biphenotypic sinonasal sarcoma (12), etc. Therefore, the immunohistochemical positivity of Pax-2 and Pax-8 should be interpreted carefully in accordance with morphological assessment to ensure an accurate diagnosis.