The study revealed that among these 12 variants, UGT1A1, along with 11 other polymorphisms found in genes associated with functions related to inflammatory pathways, immune response, and cellular and genomic stability (such as CASP8, CYP2E1, CYP19A1, IL1A, IL4, MDM2, NFKB1, PAR1, TP53, TYMS, and XRCC1) play a role in the development of both colorectal and gastric cancers. The gene discussed is UGT1A1; the disease is gastric cancer.