The most prevalent treatment-related AEs of any grade included an increase in aspartate aminotransferase (AST) (n = 68, 82.92% in the T+T+I group; n = 35, 67.31% in the T+T group), an increase in alanine aminotransferase (ALT) (n = 52, 63.41% in the T+T+I group; n = 28, 53.84% in the T+T group), pyrexia (n = 40, 48.78% in the T+T+I group; n = 34, 65.38% in the T+T group), and hypertension (n = 35, 42.68% in the T+T+I group; n = 21, 40.38% in the T+T group). This evidence concerns the gene GPT and Fever.