Clear cell renal cell carcinoma (ccRCC) is characterized by its high vascularization, primarily due to the inactivation of the von Hippel–Lindau (VHL) tumor suppressor gene, leading to the overexpression of hypoxia‐inducible factor (HIF) and vascular endothelial growth factor (VEGF) [1]. This evidence concerns the gene VEGFA and nonpapillary renal cell carcinoma.