To this end, A549 cells were treated with si_control, si_KRT6A, or siRNA targeting vATPase subunit ATP6V1B2 gene (si_ATP6V1B2) for 48 h, followed by infection with WSN (H1N1) virus at an MOI of 50 in the presence of cycloheximide (CHX) to inhibit the synthesis of new proteins. The gene discussed is ATP6V1B2; the disease is infection.