In patients who received a platelet transfusion, the following laboratory parameters, s ascites (41.2%), gall bladder wall thickening/edema (30.4%), pleural effusion (25.5%), packed cell volume (PCV) (42.5%), hemoglobin levels (14.4 g/dL), activated partial thromboplastin time (aPTT) (37.2 s), AST2/ALT levels (338.5 U/L), platelet count (26,473.5 cells/mm3), NS1 antigen positivity (91.17%), and IgM and IgG positivity rates (35.29% and 12.74%, respectively) were significant in comparison to those in patients with no platelet transfusion. The gene discussed is CD40LG; the disease is Pleural effusion.