INSR and gestational diabetes: The MD is suggested to have a protective effect on GDM mediated through a high intake of polyphenols present in key components of the diet, such as extra virgin olive oil, nuts, and fruits and vegetables, by improving insulin sensitivity, lowering glycemic load, activating insulin receptors and stimulating insulin secretion, modulated glucose release resulting in the uptake of glucose in the insulin-sensitive tissues [76], and therefore controlling eGWG.