IFNL1 and coinfection: However, H3N2 (OK/483) infection showed trends of upregulation in cytokine induction including IFN-α, IFN-β, IFN-λ1, IFN-λ2/3, and IP-10, while co-infection with SCoV2/BA.1 reduced the levels of these cytokines and chemokines.