By binding to the ALX/FPR2 receptor (Lipoxin A4 receptor), LXA4 exerts its pro-resolving effects, including (i) the inhibition of pro-inflammatory cytokine release (e.g., TNF-α, IL-1β, IL-6), (ii) reductions in microglial and astrocytic hyperactivation, (iii) the promotion of phagocytosis of beta-amyloid plaques, and (iv) the protection of neuronal integrity by preventing oxidative stress and apoptosis. Here, FPR2 is linked to amyloidosis.