The common genetic pathways that are shared between T2D and BC are insulin-like growth factor 1 (IGF-1), adipokines and the release of pro-inflammatory adiponectin/leptin, and a weakened immune response brought on by increased levels of pro-inflammatory cytokines like tumor necrosis factor-α (TNF-α) [25,26,27]. This evidence concerns the gene ADIPOQ and breast cancer.