We employed an unbiased chemogenomic screening strategy in our GBM stem cell model system, using isogenic ‘kinase-deficient’ FAK cells (FAK-KD) vs. wild type (FAK-WT) derived from previously established NPE parental cells (NF1del, PTENdel, EGFRvIII) [32]. Here, PTK2 is linked to glioblastoma.