Of the 1807 specimens processed from the patients with acute viral hepatitis at a tertiary care hospital in Western India, 6.7% (120/1807), 8.5% (154/1807), and 0.6% (11/1807) were positive for only IgM anti-HAV antibodies, only IgM anti-HEV antibodies, and both antibodies, respectively [135]. The gene discussed is CD40LG; the disease is viral hepatitis.