Based on their results and considering the mechanism of NIR-PIT targeting specific proteins on the cancer cell membrane, the targetable proteins are EGFR (expression rate: 66.7%), cMET (31.8%), PDL-1 (22%), PGP (20.1%) for non-small cell lung cancer (NSCLC), HER2 (23.3%) and EGFR (18.8%) for breast cancer, and cMET (36.4%) for melanoma [104]. This evidence concerns the gene CD274 and cancer.