Through protein–protein integration analyses, we revealed the top ten possible target genes implicated in the treatment of hypertension, including AGTR1, ADRB2, ACE, ADRA1A, ADRB1, and so on, as mentioned in Figure 2B. However, among these, only two proteins, ACE and CA-I, emerged as significant targets based on their strong binding scores with the ginseng-derived compounds. Here, ACE is linked to hypertensive disorder.