IL1B and Seizure: The content of cytokines in the hippocampal homogenates was then determined by ELISA; it was found that G. capense can reduce excitotoxic brain damage caused by interleukin-1 beta (IL-1β) and reduce the expression level of the apoptosis protein caspase-3 in the hippocampus of rats, thereby reducing the incidence of epilepsy in rats with recurrent febrile seizures [58].