This oxidative stress not only activates several inflammatory factors, including C-reactive protein, inflammasome protein 3 (NLRP3), tumor necrosis factor alpha (TNFα), and nuclear factor kappa B (NF-kB) [6], but also increases low-density lipoproteins (LDL) and HDL oxidation together with endothelial dysfunction, favoring the formation of atheroma [9]. The gene discussed is TNF; the disease is endothelial dysfunction.