Fu Jun et al. used RNA sequencing combined with molecular docking technology to reveal that it can alleviate LPS/D-GaIN-induced ALI by acting on P65 and JNK receptors, and used quantitative Polymerase Chain Reaction technology to show that ACE may also exert anti-inflammatory effects by inhibiting key targets in the Toll-like receptor signaling pathway to alleviate alcohol liver disease. The gene discussed is ACE; the disease is alcoholic liver diseases.