Similarly to other tissues, levels of TRPV1-associated kinases such as pPKA, pPI3K, and pPKC all increased after ICS-induced fibromyalgia; these effects were alleviated by EA and in Trpv1−/− mice (Figure 4C–E, # p < 0.05, n = 6). This evidence concerns the gene TRPV1 and fibromyalgia.