IL1B and myositis disease: There are other relevant biomarkers, which are related to disease activity, such as cytokines (IL-1β, IL-6, IL-8, IFNα), myeloid cell markers, myositis specific antibodies, or Type I interferon score, which measures the upregulation of type I IFN-stimulated genes (ISGs) in peripheral blood, skin, and muscle [22,23].