AKT1 and atherosclerosis: Of the 65 significantly altered pathways (p < 0.05) in the MP + DEHP group, the most prominent included cancer pathways (mmu05200, 62 DEGs), alcoholic liver disease (mmu04936, 21 DEGs), fluid shear stress and atherosclerosis (mmu05418, 23 DEGs), the PI3K-Akt signaling pathway (mmu04151, 39 DEGs), and the MAPK signaling pathway (mmu04010, 36 DEGs) (Figure 3C).