However, when NK-92 cells were co-cultured with MCP1 shRNA-transfected HCC Luc-SK-Hep1 cells, only NKp44 was significantly expressed on the surface of NK cells compared to the co-culture with shcontrol under hypoxia (Figure 6G; shcontrol 51.64%, shMCP1 67.60%; * p < 0.05). The gene discussed is CCL2; the disease is hepatocellular carcinoma.